If patient plasma reacts positively with all tested cells, what is the likely antibody if the results are negative after chemical treatment?

When patient plasma reacts positively with all tested cells, it suggests the presence of a broad specificity antibody that is capable of reacting with multiple red blood cell antigens. In this scenario, the antibody is usually a low-incidence or rare antibody.

The presence of a specific antibody is often confirmed through various tests, including chemical treatments. If the results remain negative after chemical treatment, it indicates that the antibody is resistant to that treatment. In this context, the anti-Lub antibody is consistent with these characteristics. The Lub antigen, found on RBCs, can lead to reactions with many cells, and anti-Lub is known to be one of the antibodies that does not react in certain chemical treatments, solidifying the likelihood of its presence in this specific case.

In comparison to the other antibodies listed, anti-Lub is classified among those that are often undetectable after certain treatments. This aligns with the interpretation of the test results and explains why anti-Lub is the likely antibody when all tested cells show reactivity in patient plasma but none after treatment. The options representing other antibodies do not specifically match the behavior of the reactivity observed in this scenario regarding resistance to the chemical treatment.