In a panel analysis, which antibody is likely present if anti-Fy3 shows a positive reaction?

In a panel analysis, if anti-Fy3 shows a positive reaction, it indicates the presence of the antigen corresponding to the antibody. Anti-Fy3 is a specific antibody against the Fy3 antigen, which is part of the Duffy blood group system. When a positive reaction is observed with anti-Fy3, it confirms that the Duffy antigen Fy3 is present on the red blood cells being tested.

The presence of anti-Fy3 is important for identifying the Duffy blood group phenotypes, particularly in transfusion and transplantation settings. This specificity is significant in determining compatibility between donors and recipients, as well as in understanding the immune response in patients.

The other options do not directly correspond with the identified reaction of anti-Fy3. Anti-Fyb would also imply the presence of the Fy3 antigen but typically would react more specifically with FyB rather than showing a distinct positive reaction solely based on Fy3. Anti-Fyx is not a standard designation for a known antibody in this context. Anti-Lea and anti-Leb pertain to the Lewis blood group system, which is unrelated to the Duffy antigens. Therefore, the correct interpretation of a positive reaction in this context is that anti-Fy3 is indeed present.