What is the amino acid sequence responsible for the M antigen?

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Prepare for the ASCP Specialist in Blood Banking Exam. Boost your knowledge with quizzes and comprehensive explanations. Get exam ready!

The amino acid sequence responsible for the M antigen is indeed characterized specifically by its unique sequence of amino acids. The M antigen is part of the MNS blood group system and is generated by a serologically significant protein found on the red blood cell membrane.

The sequence Ser-Ser-Thr-Thr-Gly is particularly relevant as it signifies the uniqueness of the M antigen, depicting the critical residues that define its structure and function. The presence of serine and threonine in the sequence contributes to the antigenic properties that can be recognized by antibodies in the immune response.

In blood bank serology, the specificity of antigens like the M antigen is crucial because even a slight alteration in the amino acid sequence can dramatically affect antigen recognition and the immune response, leading to complications in transfusions and compatibility. Thus, understanding the correct sequence of amino acids for the M antigen is vital for immunohematology procedures and ensuring safe blood transfusions.

The other options represent different sequences that do not correspond to the recognized structure of the M antigen, highlighting the importance of the identified sequence in antigenicity and immunogenicity.

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