What is the typical rescreening interval for antibodies in pregnant women?

The appropriate rescreening interval for antibodies in pregnant women is typically once after 28 weeks of gestation. This timing is based on the understanding that antibody development can occur at various stages during pregnancy, and it is critical to monitor for any new antibody formation that could affect the fetus. By 28 weeks, the risk of hemolytic disease of the fetus and newborn increases, making this rescreening essential for managing maternal and fetal health.

This practice aligns with guidelines that emphasize the need for ongoing assessment of maternal antibodies as pregnancy progresses. Reassessing at this point allows healthcare providers to identify any potential issues well ahead of delivery, thus enabling appropriate interventions if necessary. Earlier and more frequent screenings, such as every appointment or every month, are generally not warranted unless indicated by other clinical factors, making the interval after 28 weeks the most practical and guideline-supported recommendation.