When testing polyagglutinable cells with a panel of lectins, which type of polyagglutination is indicated if T is present?

The presence of T antigen indicates a specific type of polyagglutination known as T polyagglutination. Polyagglutinable cells exhibit abnormal agglutination patterns when exposed to certain lectins due to changes in their surface antigens.

In the context of blood banking and serology, T polyagglutination is characterized by the expression of T antigens on red blood cells (RBCs). The T antigen is a carbohydrate structure that can cause these cells to agglutinate in the presence of specific lectins, most notably from the plant Triticum vulgaris (wheat germ agglutinin). The recognition of this antigen during testing helps in diagnosing and understanding various hematological conditions.

Understanding the role of T antigens in agglutination aids in differentiating from other types such as Tk, Tn, and Th, which are associated with different abnormal expressions or mutations in the glycoproteins and glycolipids on the RBC surface. This knowledge is crucial for blood transfusion practices and ensuring compatibility between donors and recipients.